Uplift Consortium

Upright radiotherapy: Learning, Innovation, Fellowship and Training

UPLIFT builds the next generation of upright radiotherapy experts by addressing key research questions related to three main pillars: treatment planning, clinical workflow and equipment design.

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research projects

all around Europe

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UPLIFT brings together 20+ partner organizations, to bring upright radiotherapy to the clinic.

Our Capabilities

Our Research Projects

Radiotherapy (RT) is one of the three main pillars of modern cancer treatment. For decades, RT has been predominantly performed with the patient in supine or prone position. Positioning the patients in upright, sitting or standing, position promises greatly reduced treatment cost, more patient comfort, and even anatomical advantages in the form of reduced motion and greater separation of critical structures. Since upright positioning enables smaller facility footprints for photon therapy, and especially for particle therapy, it is a key to global access to modern treatment options. It therefore comes at no surprise that, with the commercial availability of upright positioning solutions and upright volumetric imaging, upright radiotherapy has enjoyed a surge in interest recently. At the same time, key questions remain in urgent need of solutions, international guidelines for upright positioning are lacking, and clinical workflow is yet tailored to supine or prone positioning. As the first clinics around the world are adopting upright technologies, there is a global need for expert professionals in industry, clinics and research to bring promised advantages from bench to bedside and carry this paradigm shift in how RT patients are treated.

UPLIFT hosts 19 exciting PhD projects across various fields and partner organisations. Explore our projects below.

Project 1: Upright time-resolved MRI

Project 2: Machine learning based deformable registration

Project 3: Advanced upright treatment planning

Project 4: Motion mitigation in upright position

Project 5: Upright particle arc therapy

Project 6: Clinical upright radiotherapy workflow at a photon centre

Project 7: Clinical upright radiotherapy workflow at a particle centre

Project 8: Quality assurance software for upright radiotherapy

Project 9: Quality assurance workflow and dosimetry

Project 10: Upright immobilization and positioning

Project 11: Design of isocentric MRI guided upright particle therapy

Project 12: Upright PET imaging

Project 13: Antropomorphic phantoms for upright treatment validation

Project 14: Patient empowerment: The human aspect of particle therapy

Project 15: Socio-economic impact analysis of upright radiotherapy

Project 16: Multimodal imaging for upright posture

Project 17: Anatomical differences analysis between upright and supine position

Project 18: Human factors and ergonomics to evaluate and improve patient positioning for upright radiotherapy

Project 19: Patient empowerment: The human aspect of radiotherapy

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Members of UPLIFT Consortium

UPLIFT brings together 15 supervising institutions from all over Europe with one aim in common: To bring upright radiotherapy to the clinic.